Ophthalmology Department, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.
J Neuroophthalmol. 2010 Mar;30(1):31-3. doi: 10.1097/WNO.0b013e3181ce18eb.
A 4-year-old healthy girl with acute visual loss in the right eye had ophthalmoscopic evidence of a swollen optic disc combined with central retinal artery and vein occlusion in the affected eye. MRI showed that the intraorbital optic nerve on the affected side was thickened and enhancing. Diffusion-weighted imaging showed restricted diffusion in the distal intraorbital segment of the optic nerve, consistent with infarction attributed to compression or inflammation of the vessels serving the optic nerve and retina. Although such clinical phenomena have been described previously, this is the first patient to demonstrate restricted diffusion in an inflammatory optic neuropathy. The presence of restricted diffusion is helpful in excluding a neoplastic cause of a thickened optic nerve.
一位 4 岁健康女孩右眼急性视力丧失，眼底检查显示视盘肿胀，受累眼的视网膜中央动脉和静脉阻塞。MRI 显示受累侧眶内视神经增粗并增强。弥散加权成像显示视神经眶内段远端弥散受限，符合压迫或炎症导致视神经和视网膜血管受累引起的梗死。尽管此前已有此类临床现象的描述，但该患者是首例显示炎症性视神经病变弥散受限的患者。弥散受限的存在有助于排除视神经增厚的肿瘤性原因。
