Inedjian J M, Thomassin J M, Danoy M C, Sermet M, Geunoun A
Service ORL, CHR Sainte-Marguerite, Marseille.
Ann Otolaryngol Chir Cervicofac. 1991;108(1):63-6.
The authors report on one case of pharyngolaryngeal extraosseous Ewing's sarcoma. This is a very rare tumor which preferentially has a paravertebral or retroperitoneal location. The difficult histological diagnosis is greatly facilitated by the use of tumoral markers. The treatment implemented consisted of a "conventional" Cisplatin 5 FU chemotherapy, which allowed an almost complete clinical recession after 3 courses, then of external radiation therapy. The evolution of these tumors still remains unpredictable. Regional metastases to the lymph nodes are rare, and they are usually remote and mainly pulmonary. Lastly, the merits of computed tomography for the follow-up of these intramural lesions of the larynx must be emphasized.
作者报告了一例咽喉部骨外尤文肉瘤。这是一种非常罕见的肿瘤,好发于椎旁或腹膜后部位。肿瘤标志物的使用极大地促进了困难的组织学诊断。所实施的治疗包括“传统的”顺铂联合5-氟尿嘧啶化疗,3个疗程后实现了几乎完全的临床消退,随后进行了外照射放疗。这些肿瘤的病程仍然难以预测。区域淋巴结转移罕见,通常为远处转移,主要是肺转移。最后,必须强调计算机断层扫描在这些喉壁内病变随访中的作用。