Shaw H J
Head and Neck Unit, Royal Marsden Hospital, London, England.
Ann Otol Rhinol Laryngol. 1991 Apr;100(4 Pt 1):268-73. doi: 10.1177/000348949110000402.
This retrospective study evaluates the use of conservation surgical salvage techniques in cases of early (T1 and T2) laryngeal cancer after full-dose external irradiation. Fifty patients in one London hospital and 68 patients in another were studied for the period 1963 to 1988. Treatment policy directed that the majority of limited glottic and supraglottic tumors should be treated initially by external irradiation. The small number of glottic treatment failures had a good chance of salvage by vertical partial laryngectomy if recurrence or a new primary was detected early. Recurrence of supraglottic cancer was salvaged occasionally by horizontal partial laryngectomy if strict indications were observed. Total laryngectomy remained the final minority salvage option.
这项回顾性研究评估了在全剂量外照射后早期(T1和T2)喉癌病例中保留性手术挽救技术的应用。1963年至1988年期间,对伦敦一家医院的50例患者和另一家医院的68例患者进行了研究。治疗策略规定,大多数局限性声门和声门上肿瘤应首先接受外照射治疗。如果早期发现复发或新发原发性肿瘤,少数声门治疗失败的病例有通过垂直部分喉切除术挽救的良好机会。如果严格遵循适应证,声门上癌复发偶尔可通过水平部分喉切除术挽救。全喉切除术仍然是最后的少数挽救选择。