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酒精中毒合并症对创伤性脑损伤后神经认知功能的影响。

The effects of alcoholism comorbidity on neurocognitive function following traumatic brain injury.

作者信息

Allen Daniel N, Goldstein Gerald, Caponigro Janelle M, Donohue Bradley

机构信息

Department of Psychology, University of Nevada Las Vegas, Las Vegas, Nevada 89154-5030, USA.

出版信息

Appl Neuropsychol. 2009 Jul;16(3):186-92. doi: 10.1080/09084280903098687.

Abstract

Alcoholism and traumatic brain injury (TBI) often produce neuropsychological deficits. However, the extent and manner by which these factors interact is unclear. In this study, it was hypothesized that alcoholism would have compounding cognitive effects in individuals with TBI and alcoholism. Participants were divided into three groups, including a patient comparison (PC) group and groups with TBI with or without alcoholism histories. Participants were administered the Wechsler Adult Intelligence Scale-Revised and major components of the Halstead-Reitan Neuropsychological Test Battery. Comparing the groups on test performance, the TBI groups performed significantly worse than the PC group but did not significantly differ from each other. Thus, the effects of TBI on cognitive function overshadow preexisting deficits from the alcoholism.

摘要

酗酒和创伤性脑损伤(TBI)常常会导致神经心理缺陷。然而,这些因素相互作用的程度和方式尚不清楚。在本研究中,研究者假设酗酒会对患有TBI和酗酒问题的个体产生复合性认知影响。参与者被分为三组,包括一个患者对照组(PC组)以及有或没有酗酒史的TBI组。对参与者进行了韦氏成人智力量表修订版以及霍尔斯特德-雷坦神经心理测验组套的主要部分测试。比较各组的测试表现,TBI组的表现显著差于PC组,但两组之间没有显著差异。因此,TBI对认知功能的影响掩盖了酗酒先前存在的缺陷。

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