Yang Xiu-Wei, Zhang Cai-Yu, Zhang Ben-Gang, Lu Yang, Luan Jiang-Wei, Zheng Qi-Tai
State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing, China.
J Asian Nat Prod Res. 2009 Aug;11(8):698-703. doi: 10.1080/10286020802619140.
A new natural coumarin, angepubebisin (1), and a new furan, angepubefurin (2), together with the five known compounds, umbelliferone, angelol B (3), ulopterol (4), peucedanol (5), and scopoletin, were isolated from the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan. The structures of angepubebisin (1) and known compounds were determined by spectroscopic methods, including IR, UV, EI-MS, HR-FTICR-MS, 1D-, and 2D-NMR spectral analyses, and angepubefurin (2) was determined by HR-FTICR-MS and X-ray diffraction analyses.
从独活（Angelica pubescens Maxim. f. biserrata Shan et Yuan）的根中分离出一种新的天然香豆素独活二氢香豆素（1）和一种新的呋喃类化合物独活呋林（2），以及五种已知化合物伞形花内酯、当归醇B（3）、异欧前胡素醇（4）、前胡醇（5）和东莨菪内酯。通过红外光谱（IR）、紫外光谱（UV）、电子轰击质谱（EI-MS）、高分辨傅里叶变换离子回旋共振质谱（HR-FTICR-MS）、一维和二维核磁共振谱（1D-、2D-NMR）等光谱方法确定了独活二氢香豆素（1）和已知化合物的结构，通过高分辨傅里叶变换离子回旋共振质谱（HR-FTICR-MS）和X射线衍射分析确定了独活呋林（2）的结构。
