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冠状动脉搭桥术后胸骨骨髓炎和纵隔炎

[Sternal osteitis and mediastinitis after coronary artery bypass graft surgery].

作者信息

Detroz B, Defraigne J O, Limet R

机构信息

Service de Chirurgie Cardiovasculaire, Centre Hospitalier Universitaire de Liège, Sart-Tilman, Belgique.

出版信息

Ann Chir. 1991;45(2):128-35.

PMID:2018332
Abstract

Between 1980 and 1987, 31 cases of osteitis (n = 9) and/or mediastinitis (n = 22) were observed after 2,801 consecutive aorto-coronary bypasses (1.1%). Three types of treatment were used: 1) sternal debridement with osteosynthesis and continuous mediastinal irrigation (n = 25); 2) sternal and mediastinal debridement with open drainage without osteosynthesis (n = 2); 3) incision and debridement of sternal abscesses (n = 4). The overall mortality was 26% (8/31), i.e. 11% (1/9) for isolated osteitis and 32% (7/22) for mediastinitis. Four factors were statistically associated with infection: reoperation for hemorrhage (19.4%, p less than 0.001); preoperative diabetes (25%, p less than 0.001), postoperative low cardiac output (55%, p less than 0.001), postoperative respiratory insufficiency (45%, p less than 0.001).

摘要

在1980年至1987年期间,连续进行2801例主动脉冠状动脉搭桥手术后,观察到31例骨炎(n = 9)和/或纵隔炎(n = 22)(发生率为1.1%)。采用了三种治疗方法:1)胸骨清创术加骨固定术及持续纵隔冲洗(n = 25);2)胸骨和纵隔清创术加开放引流且无骨固定术(n = 2);3)胸骨脓肿切开清创术(n = 4)。总体死亡率为26%(8/31),即孤立性骨炎为11%(1/9),纵隔炎为32%(7/22)。有四个因素与感染在统计学上相关:因出血再次手术(19.4%,p<0.001);术前糖尿病(25%,p<0.001),术后低心排血量(55%,p<0.001),术后呼吸功能不全(45%,p<0.001)。

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