[Investigation of the influence of temperature on polyelectrolyte microcapsules containing and not containing proteins].

Using the methods of light scattering and optical microscopy, data on the thermosensitivity of hollow microcapsules generated by alternative layers of poly(allylamine) and poly(sterenesulfonate) polyelectrolyte and microcapsules with included polyelectrolyte complexes and proteins have been obtained. It has been shown that all three types of capsules shrink with increasing temperature and the time interval of thermal influence, and their diameter decreases. The thermosensitivity has been estimated by means of the temperature factor of shell shrinkage (Ec). For all three types of the microcapsules containing from 6 to 10 layers in the shell, the phenomenon of the thermosensitivity alternation depending on the number of shell layers was revealed. With an odd number of the shell layers, the shrinkage is stronger than with an even number. Using the transport proteins of blood hemoglobin and bovine serum albumin as an example, the dependence of the thermosensitivity of microcapsules on the quantity, the degree of ionization, and the conformational state of the incapsulating protein was investigated.