Obrink K J, Waller M
Institute of Physiology and Medical Biophysics, University of Uppsala, Uppsala, Sweden.
Scand J Gastroenterol. 1967;2(1):44-8. doi: 10.3109/00365526709180046.
In a Heidenhain pouch dog the K(+) concentration of the gastric juice was analyzed after continuous intravenous injections of histamine. The steady states of the secretion rates and the changing over from different steady states were studied. The old observation that the K(+) concentration is independent of the secretion rate in the steady state was confirmed, but it was also found that during an increase of the secretion rate the K(+) concentration in the juice showed a transient increase. In changing the secretion rate to a lower steady level the K(+) concentration showed a similar deviation in the opposite direction before returning to its steady-state level. It is suggested that this phenomenon is due to a loss and uptake of K(+) by the mucosa when stimulation is started or stopped.
在一只海登海因袋犬身上，在持续静脉注射组胺后分析胃液的钾离子浓度。研究了分泌速率的稳态以及从不同稳态的转变。过去关于钾离子浓度在稳态下与分泌速率无关的观察结果得到了证实，但同时也发现，在分泌速率增加期间，胃液中的钾离子浓度出现短暂升高。当将分泌速率改变到较低的稳态水平时，钾离子浓度在恢复到稳态水平之前，在相反方向上出现了类似的偏差。有人认为，这种现象是由于刺激开始或停止时黏膜对钾离子的丢失和摄取所致。
