Marangi Giovanni Francesco, Toto Vito, Poccia Igor, Gigliofiorito Pierluigi, Brunetti Beniamo, Persichetti Paolo
Department of Plastic and Reconstructive Surgery, University Campus Bio-Medico of Rome, Via Alvaro del Portillo, 00128 Rome, Italy.
Cases J. 2009 Sep 8;2:8751. doi: 10.1186/1757-1626-0002-0000008751.
Granular cell tumour, also known as Abrikossoff's tumour, is a rare entity occurring in the skin as well as in internal organs, more common among the third to fifth decade of life. It has often been described as a peripheral neuroectodermal tumour and its clinical behaviour is usually benign although malignant and multifocal forms are also known to occur.
We report a case of multiple granular cell tumour in a 17-year-old Caucasian woman who presented with a nodular lesion in the popliteal cave, diagnosed as an Abrikossoff's Tumour, followed 2 years later by another soft tissue mass in the neck.
This case is quite rare: only a few cases were presented in literature with an extended period of time before the clinical presentation of subsequent disease.
颗粒细胞瘤,也称为阿布里科索夫瘤,是一种罕见的肿瘤,可发生于皮肤及内脏器官,多见于30至50岁人群。它常被描述为一种外周神经外胚层肿瘤,其临床行为通常为良性,不过也有恶性和多灶性形式的报道。
我们报告一例17岁白种女性的多发性颗粒细胞瘤病例,该患者腘窝处出现结节性病变,诊断为阿布里科索夫瘤,两年后颈部又出现一个软组织肿块。
该病例十分罕见:文献中仅有少数病例报道了后续疾病临床表现出现前有较长的时间间隔。