Institute of Ecological Science, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Ecotoxicol Environ Saf. 2010 Jul;73(5):1051-6. doi: 10.1016/j.ecoenv.2010.02.002. Epub 2010 Feb 24.
For 7 weeks, we studied the effects on body size and growth rate of Folsomia candida exposed to nickel and chlorpyrifos and their mixtures in a natural Lufa 2.2 soil. Nickel significantly reduced the development of body size of the springtails, although no complete dose-response curve was obtained. Chlorpyrifos did not influence the springtail growth when applied alone, but significantly reduced the growth retardation induced by nickel. We showed that by monitoring the development of toxicity in time for both the single compounds and the mixtures it was possible to determine mixture interactions even when no complete dose-response curves were available for all mixture components.
在 7 周的时间里，我们研究了在天然 Lufa 2.2 土壤中，暴露于镍和毒死蜱及其混合物中的 Folsomia candida 对体型大小和生长速度的影响。镍显著降低了跳虫的体型发育，尽管没有获得完整的剂量反应曲线。单独施用毒死蜱不会影响跳虫的生长，但会显著降低镍诱导的生长迟缓。我们表明，通过及时监测单一化合物和混合物的毒性发展，即使对于所有混合物成分都没有完整的剂量反应曲线，也可以确定混合物的相互作用。
