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在有序梳状聚合物表面抑制细菌黏附。

Inhibition of bacterial adhesion on well ordered comb-like polymer surfaces.

机构信息

Department of Chemical and Biological Engineering, Seoul National University, 599 Gwanangno, Gwanak-gu, Seoul 151-744, Republic of Korea.

出版信息

Colloids Surf B Biointerfaces. 2010 Jun 1;77(2):191-9. doi: 10.1016/j.colsurfb.2010.01.023. Epub 2010 Feb 4.

DOI:10.1016/j.colsurfb.2010.01.023
PMID:20185280
Abstract

The surfaces of comb-like poly(oxyethylene) derivatives with n-alkylsulfonyl side groups were more effective at reducing Pseudomonas aeruginosa adhesion than the surfaces of common materials such as polystyrene, poly(methyl methacrylate), poly(dimethylsiloxane), fluorinated polyacrylate, and glass. When the comb-like poly(oxyethylene) was mixed with polystyrene and poly(methyl methacrylate), the topology and roughness of the surfaces varied according to the mixture compositions. However the surface energies of the mixtures were close to that of the comb-like poly(oxyethylene) in the range of 21-23 mN/m and bacterial adhesion resistances of the mixture surfaces were also comparable to that of the pure comb-like poly(oxyethylene) surface.

摘要

带有正烷基磺酰侧基的梳状聚(氧化烯)衍生物的表面比聚苯乙烯、聚甲基丙烯酸甲酯、聚二甲基硅氧烷、氟化聚丙烯酸酯和玻璃等常见材料更能有效降低铜绿假单胞菌的黏附。当梳状聚(氧化烯)与聚苯乙烯和聚甲基丙烯酸甲酯混合时,表面的拓扑结构和粗糙度会根据混合物的组成而变化。然而,混合物的表面能在 21-23 mN/m 范围内接近梳状聚(氧化烯),混合物表面的细菌黏附阻力也与纯梳状聚(氧化烯)表面相当。

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