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健康求职者效应、工作选择与哮喘青年的吸入暴露。

Healthy hire effect, job selection and inhalation exposure among young adults with asthma.

机构信息

Dept of Medicine and Public Health, Unit of Occupational Medicine, University Hospital of Verona, University of Verona, 37129 Verona, Italy.

出版信息

Eur Respir J. 2010 Sep;36(3):517-23. doi: 10.1183/09031936.00125709. Epub 2010 Feb 25.

Abstract

The aim of the present study was to assess whether asthma onset prior to entering the workforce influences whether a person holds a subsequent job with asthma-related inhalation exposures. The data of 19,784 adults from the European Community Respiratory Health Survey were analysed. For each respondent, a current or previously held job was linked to a job exposure matrix assigning high, low or no exposure to dust, gases or fumes. Jobs were also categorised according to the risk of exposures related to occupational asthma. Associations between asthma and subsequent occupational exposures were assessed using logistic regression models, with a random intercept for study centre and fixed adjustment for age, sex, type of study sample and smoking status. Of the respondents, 8% (n = 1,619) reported asthma with onset before completion of full-time education. This population was at decreased risk of having a job with high (odds ratio 0.79; 95% confidence interval 0.68-0.92) or low (0.91; 0.80-1.03) exposure to dust, gases or fumes. The associations were consistent across exposure types (dusts, gases or fumes) and for jobs with a high risk of occupational asthma. Adults with asthma onset prior to entering the workforce may be less likely to hold jobs involving inhalation exposures.

摘要

本研究旨在评估在进入劳动力市场之前是否患有哮喘是否会影响一个人在随后的工作中是否会接触到与哮喘相关的吸入性暴露。分析了来自欧洲社区呼吸健康调查的 19784 名成年人的数据。对于每个受访者,当前或以前的工作都与职业暴露矩阵相关联,该矩阵将粉尘、气体或烟雾的高、低或无暴露分配给工作。根据与职业性哮喘相关的暴露风险,还对工作进行了分类。使用逻辑回归模型评估哮喘与随后的职业暴露之间的关联,为研究中心设置随机截距,并固定调整年龄、性别、研究样本类型和吸烟状况。在受访者中,8%(n=1619)报告称在完成全日制教育之前就患有哮喘。该人群从事高(比值比 0.79;95%置信区间 0.68-0.92)或低(0.91;0.80-1.03)粉尘、气体或烟雾暴露的工作的风险降低。这些关联在暴露类型(粉尘、气体或烟雾)和高职业性哮喘风险的工作中是一致的。在进入劳动力市场之前就患有哮喘的成年人可能不太可能从事涉及吸入性暴露的工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c03/4517194/e3cb6e1b82ff/nihms708830f1.jpg

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