Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Anesth Analg. 2010 Mar 1;110(3):839-42. doi: 10.1213/ANE.0b013e3181cde5a5.
Multiple pharmaceutical products contain excipients, or additive chemicals, to improve stability, bioavailability, antimicrobial activity, or palatability. Two of the most common excipients are propylene glycol and parabens. We report the successful anesthetic management of a patient with idiosyncratic reactions to prescribed and over-the-counter medications containing propylene glycol and parabens.
多种药物制剂含有辅料或添加剂化学物质，以提高稳定性、生物利用度、抗菌活性或可接受性。两种最常见的赋形剂是丙二醇和对羟基苯甲酸酯。我们报告了一例对含有丙二醇和对羟基苯甲酸酯的处方药和非处方药均有特异反应的患者的成功麻醉管理。
