Università Sapienza di Roma, II Facoltà di Medicina e Chirurgia, Ospedale Sant'Andrea, via di Grottarossa 1035, Rome, Italy.
Anesth Analg. 2010 Mar 1;110(3):852-4. doi: 10.1213/ANE.0b013e3181cc55a5.
We present a case of community-acquired methicillin-resistant Staphylococcus aureus necrotizing pneumonia, Panton-Valentine leukocidin positive, in a woman at 14 weeks of pregnancy. To our knowledge, this is the first case reporting this critical lung infection occurring during an early phase of pregnancy. This case study alerts physicians to the increasing worldwide spread of these uncommon yet virulent and potentially lethal infections. In our patient, antibiotic therapy with linezolid plus rifampin started at 14 weeks of pregnancy had a successful outcome without inducing toxicity or teratogenesis in the fetus.
我们报告了一例社区获得性耐甲氧西林金黄色葡萄球菌坏死性肺炎,产毒型杀白细胞素阳性,发生于妊娠 14 周的女性。据我们所知,这是首例报道的在妊娠早期发生的这种严重肺部感染。本病例研究提醒医生注意这些罕见但毒力强且可能致命的感染在全球范围内的传播日益增多。在我们的患者中,妊娠 14 周时开始使用利奈唑胺加利福平的抗生素治疗取得了成功的结果,未在胎儿中引起毒性或致畸作用。