Catho G, Gillet Y, Dumitrescu O, Lina G, Labbé G, Bellon G, Reix P
Service de pédiatrie, pneumologie, allergologie, mucoviscidose, hôpital Femme-Mère-Enfant, hospices civils de Lyon, 59, boulevard Pinel, 69677 Bron, France.
Arch Pediatr. 2011 Oct;18(10):1090-4. doi: 10.1016/j.arcped.2011.07.019. Epub 2011 Sep 1.
Necrotizing Staphylococcus aureus Panton-Valentine leukocidin (SA-PLV+) accounts for less than 1% of community-acquired lung diseases in children and young adults. Neonatal cases are exceptional. We report the observations of two newborn female twins, who were not breastfed, presenting a necrotizing lung disease due to the same strain of SA-PVL+ despite nasal decolonization measures taken. These two cases are informative and bring to light (1) the possibility of severe SA-PVL+ lung infections in young infants and (2) their strictly intrafamilial mode of transmission for which eradication measures were ineffective.
坏死性金黄色葡萄球菌杀白细胞素（SA-PLV+）在儿童和年轻成人社区获得性肺部疾病中所占比例不到1%。新生儿病例极为罕见。我们报告了两名未进行母乳喂养的新生女双胞胎的观察情况，尽管采取了鼻腔去定植措施，但她们因同一株SA-PVL+而出现坏死性肺部疾病。这两个病例具有启发性，揭示了（1）幼儿发生严重SA-PVL+肺部感染的可能性，以及（2）其严格的家庭内传播模式，针对这种传播模式的根除措施无效。
