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Molecular biology. Reliable noise.

作者信息

Levens David, Gupta Ashutosh

机构信息

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

出版信息

Science. 2010 Feb 26;327(5969):1088-9. doi: 10.1126/science.1187268.

DOI:10.1126/science.1187268

PMID:20185714

Abstract

摘要

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引用本文的文献

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Molecular biology. Reliable noise.

作者信息

Levens David, Gupta Ashutosh

机构信息

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

出版信息

Science. 2010 Feb 26;327(5969):1088-9. doi: 10.1126/science.1187268.

DOI:10.1126/science.1187268

PMID:20185714

Abstract

摘要

相似文献

Molecular biology. Reliable noise.

Science. 2010 Feb 26;327(5969):1088-9. doi: 10.1126/science.1187268.

Noise can induce bimodality in positive transcriptional feedback loops without bistability.

Science. 2010 Feb 26;327(5969):1142-5. doi: 10.1126/science.1178962.

Evaluation of the performance of mechanisms for noise attenuation in a single-gene expression.

J Theor Biol. 2005 Jul 21;235(2):241-64. doi: 10.1016/j.jtbi.2005.01.007. Epub 2005 Feb 25.

Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system.

Biochem J. 2004 Aug 15;382(Pt 1):43-50. doi: 10.1042/BJ20031760.

Transcriptional regulatory networks in Saccharomyces cerevisiae.

Science. 2002 Oct 25;298(5594):799-804. doi: 10.1126/science.1075090.

Genetic properties influencing the evolvability of gene expression.

Science. 2007 Jul 6;317(5834):118-21. doi: 10.1126/science.1140247. Epub 2007 May 24.

Stochastic switching in gene networks can occur by a single-molecule event or many molecular steps.

J Mol Biol. 2010 Feb 12;396(1):230-44. doi: 10.1016/j.jmb.2009.11.035. Epub 2009 Nov 18.

Simulation of genetic networks modelled by piecewise deterministic Markov processes.

IET Syst Biol. 2008 May;2(3):113-35. doi: 10.1049/iet-syb:20070045.

Transcriptional regulation of the hepatocyte growth factor (HGF) gene by the Sp family of transcription factors.

Oncogene. 1997 Jun 26;14(25):3039-49. doi: 10.1038/sj.onc.1201152.

Genetic networks. Small numbers of big molecules.

Science. 2002 Aug 16;297(5584):1129-31. doi: 10.1126/science.1075988.

引用本文的文献

Cellular heterogeneity mediates inherent sensitivity-specificity tradeoff in cancer targeting by synthetic circuits.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8133-8. doi: 10.1073/pnas.1604391113. Epub 2016 Jul 6.

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models.

Nat Commun. 2015 Jun 15;6:7404. doi: 10.1038/ncomms8404.