Arai Atsushi, Morishita Akitsugu, Hanada Yusei, Aihara Hideo
Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Hyogo.
Neurol Med Chir (Tokyo). 2010;50(2):158-61. doi: 10.2176/nmc.50.158.
A 61-year-old female, previously treated for lung cancer, presented with a rare case of metastasis directly to the optic chiasm manifesting as visual deficits. Magnetic resonance imaging revealed a suprasellar mass similar to an optic glioma. At surgery, the optic chiasm appeared swollen with hypervascularity over the surface. The bilateral optic nerves and the pituitary stalk appeared normal. A small incision was made on the superior surface of the chiasm and biopsy specimens were taken. The histological diagnosis was adenocarcinoma, which was consistent with the primary lung cancer. She received whole brain irradiation, resulting in mild improvement of her vision. Suprasellar metastatic tumors to the pituitary gland, pituitary stalk, and hypothalamus are well documented, but solitary metastasis within the optic chiasm should be considered as one of several differential diagnoses of suprasellar tumors, in patients with or without a history of treated cancer.
一名61岁女性,曾接受过肺癌治疗,出现了罕见的直接转移至视交叉的病例,表现为视力缺陷。磁共振成像显示鞍上有一个类似于视神经胶质瘤的肿块。手术中,视交叉看起来肿胀,表面血管增多。双侧视神经和垂体柄看起来正常。在视交叉上表面做了一个小切口并取了活检标本。组织学诊断为腺癌,与原发性肺癌一致。她接受了全脑照射,视力略有改善。鞍上转移瘤累及垂体、垂体柄和下丘脑已有充分记录,但在有或无癌症治疗史的患者中,视交叉内的孤立转移应被视为鞍上肿瘤的几种鉴别诊断之一。