Hongoh Sachiko, Nomoto Takeshi, Kawakami Masayoshi, Hanai Kazuya, Inatsuchi Hiroaki, Terachi Toshiro
The Department of Urology, Tokai University.
Hinyokika Kiyo. 2010 Feb;56(2):107-10.
A 39-year-old man visited our clinic with gross hematuria. Cystoscopy revealed a papillary tumor at the urinary bladder dome. Abdominal magnetic resonance imaging (MRI) and computed tomography(CT) demonstrated a tumor extending from the umbilicus to the bladder dome. Transurethral resection of bladder tumor (TUR-Bt) was performed and histopathological findings revealed adenocarcinoma. Chest CT and examination of the upper gastrointestinal did not reveal any abnormal findings. The tumor was diagnosed as stage IIIA urachal carcinoma, and en bloc segmental resection was performed. About 10 months later, chest CT demonstrated multiple lung metastases. After two courses of combination chemotherapy with methotrexate (MTX), 5-fluorouracil (5-FU), epirubicin (epiADM), and cisplatin (CDDP), the multiple lung metastases completely disappeared. The patient has survived 23 months to date with no evidence of disease and is receiving adjuvant chemotherapy with tegafur uracil.
一名39岁男性因肉眼血尿前来我院就诊。膀胱镜检查发现膀胱顶部有一个乳头状肿瘤。腹部磁共振成像（MRI）和计算机断层扫描（CT）显示肿瘤从脐部延伸至膀胱顶部。行经尿道膀胱肿瘤切除术（TUR-Bt），组织病理学检查结果显示为腺癌。胸部CT和上消化道检查未发现任何异常。该肿瘤被诊断为ⅢA期脐尿管癌，并进行了整块节段性切除。大约10个月后，胸部CT显示多发肺转移。在接受了两疗程由甲氨蝶呤（MTX）、5-氟尿嘧啶（5-FU）、表柔比星（表阿霉素）和顺铂（CDDP）组成的联合化疗后，多发肺转移灶完全消失。患者至今已存活23个月，无疾病迹象，目前正在接受替加氟尿嘧啶辅助化疗。
