Department of Neurology, University of Maryland School of Medicine, Baltimore, Maryland 21210, USA.
Mov Disord. 2010;25 Suppl 1:S131-5. doi: 10.1002/mds.22789.
Even with optimal therapy, it is inevitable that the symptoms of Parkinson's disease (PD) progress and gradually result in disability in the performance of daily activities. Delay and prevention of disability is among the highest priorities in the clinical management of PD. Understanding the association between the diverse symptoms of PD and the emerging disability is fundamental to minimizing functional limitations. This article differentiates disability from impairment and quality of life and explores the relationship between the specific impairments of PD and resulting disability. Identifying appropriate tools for outcomes measurement and impediments to accurate assessment of disability are also reviewed.
即使采用了最佳的治疗方法，帕金森病（PD）的症状也不可避免地会逐渐进展，导致日常活动能力逐渐丧失。因此，延迟和预防残疾是 PD 临床管理的重中之重。了解 PD 的各种症状与新出现的残疾之间的关系，对于最大限度地减少功能限制至关重要。本文将残疾与损伤和生活质量区分开来，并探讨了 PD 的特定损伤与导致的残疾之间的关系。同时还探讨了如何选择合适的结果测量工具以及如何准确评估残疾。
