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[生长因子对肌腱愈合的影响]

[Effects of growth factors on tendon healing].

作者信息

Geng Zhen, Wang Chen

机构信息

Department of Orthopedics, Affiliated Zhongda Hospital of Southeast University, Nanjing Jiangsu, 210009, P.R. China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2010 Feb;24(2):239-42.

Abstract

OBJECTIVE

To review the research and delivery methods of growth factors in tendon injuries, and to point out the problems at present as well as to predict the trend of development in this field.

METHODS

Domestic and international literature concerning growth factors to enhance tendon and ligament healing in recent years was extensively reviewed and thoroughly analyzed.

RESULTS

Cell growth factor could promote tendon healing, improve the mechanical properties as well as reduce the adhesion postoperatively. The use of transgenic technology mediating cell factors to promote tendon repair shows its advantages in many ways.

CONCLUSION

The growth factors play a vital role in tendon healing. Reasonable treatment of growth factors through direct application or gene transfer techniques is of great value for the healing process.

摘要

目的

综述生长因子在肌腱损伤中的研究及应用方法,指出当前存在的问题并预测该领域的发展趋势。

方法

广泛查阅并深入分析近年来国内外有关生长因子促进肌腱和韧带愈合的文献。

结果

细胞生长因子可促进肌腱愈合,改善力学性能,并减少术后粘连。利用转基因技术介导细胞因子促进肌腱修复在多方面显示出优势。

结论

生长因子在肌腱愈合中起着至关重要的作用。通过直接应用或基因转移技术对生长因子进行合理处理,对愈合过程具有重要价值。

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