Bancu L, Bara T, Jimboreanu O, Mureşan M, Bancu S
Clinica Medical nr. 2. Spitalul Universitar Judeţean de Urgenţä Tg. Mureş.
Chirurgia (Bucur). 2009 Nov-Dec;104(6):719-21.
The aim of the study is to evaluate the outcome of a selected group of 24 patients who underwent surgery for refractory ascites, in a 10 years period, 1995-2005.
Alcoholic cirrhosis (n=18), inferior cava thrombosis (n=2), splenic vein thrombosis (n=1), cryptogenic cirrhosis (n=3), with association of variceal bleeding and refractory ascites. The surgical procedures consisted of porto-sistemic shunts (n=12), peritoneo-saphene shunts (n=10), mesenterico-caval shunt (n=1), mesenterico-right atrium shunt (n=1). Early results were very good: no postoperative mortality, no general haemo-dinamic failure, no renal fonctional failure, no encephalopathy. 7 of 10 peritoneo-saphene shunts had an excelent evolution, but in three cases the results were unsatisfactory, the patients continuing the medical treatment. Except one patient who died after 2 years, for B virus and alcoholic abuse, all the patients survived 5 or more years. There was not evidence of digestive hemorrhage or uncontrolable encephalopathy and thrombocytopenia. The grade of esophageal varices was mantained lower than II, ascites remained minimum or absent, and biological parameters were normal or slightly elevated.
In the absence of the technical and economical possibilities of TIPS and liver transplantation, surgery for intractable ascites is a good option in selected patients, especially in the absence of viruses and alcohol consumption, and can improve complications in the natural evolution of the disease.
本研究旨在评估1995年至2005年期间接受难治性腹水手术的24例特定患者的治疗结果。
酒精性肝硬化(n = 18)、下腔静脉血栓形成(n = 2)、脾静脉血栓形成(n = 1)、隐源性肝硬化(n = 3),伴有静脉曲张破裂出血和难治性腹水。手术方式包括门体分流术(n = 12)、腹膜-大隐静脉分流术(n = 10)、肠系膜-腔静脉分流术(n = 1)、肠系膜-右心房分流术(n = 1)。早期结果非常好:无术后死亡、无全身血液动力学衰竭、无肾功能衰竭、无肝性脑病。10例腹膜-大隐静脉分流术中7例进展良好,但3例结果不理想,患者继续接受药物治疗。除1例因B病毒感染和酒精滥用在2年后死亡外,所有患者均存活5年或更长时间。无消化出血、无法控制的肝性脑病和血小板减少的证据。食管静脉曲张程度维持在II级以下,腹水保持最少或消失,生物学指标正常或略有升高。
在没有经颈静脉肝内门体分流术(TIPS)和肝移植的技术及经济条件时,难治性腹水手术对特定患者是一个不错的选择,尤其是在没有病毒感染和饮酒的情况下,并且可以改善疾病自然发展过程中的并发症。