Rousseau H, Vinel J P, Maquin P, Suc B, Bilbao I, Longo J, Fourtanier G, Joffre F
Ann Radiol (Paris). 1994;37(5):316-22.
From the first one hundred consecutive patients treated by transjugular intrahepatic portosystemic shunt (TIPS), 12 subsequently underwent liver transplantation (a mean of 103 +/- 109 days after TIPS). Fourteen TIPS were created in 12 patients, with advanced cirrhosis (Child B = 5, C = 7) and portal hypertension. Seven patients presented either active variceal hemorrhage or refractory variceal bleeding, and 5 cases of refractory ascites. The shunt could be performed in all cases. Two patients experienced rebleeding (one after a shunt obstruction) and were successfully treated by insertion of a second TIPS. A histological study was performed in 10 cases. The shunt was patent in all cases (except in one case previously described), and the endoluminal surface was covered by a connective tissue layer and a new endothelium. We therefore conclude that this method is a safe and effective therapy for complications of portal hypertension, in patients referred for liver transplantation.
在首批接受经颈静脉肝内门体分流术（TIPS）治疗的100例连续患者中，有12例随后接受了肝移植（TIPS术后平均103±109天）。12例患者共进行了14次TIPS手术，这些患者均患有晚期肝硬化（Child B级5例，C级7例）和门静脉高压。7例患者出现活动性静脉曲张出血或难治性静脉曲张出血，5例患者出现难治性腹水。所有病例均能成功实施分流术。2例患者发生再出血（1例在分流道梗阻后），通过植入第二个TIPS成功治疗。对10例患者进行了组织学研究。所有病例（除1例先前描述的病例外）分流道均通畅，腔内表面覆盖有结缔组织层和新的内皮。因此，我们得出结论，对于转诊接受肝移植的门静脉高压并发症患者，该方法是一种安全有效的治疗方法。
