National Atomic Energy Commission, National Research Council, Salta, Argentina.
Microsc Microanal. 2010 Apr;16(2):132-6. doi: 10.1017/S1431927610000097. Epub 2010 Feb 26.
The morphology of the osteocyte lacuno-canalicular system at the bone-biomaterial implant-interface has not been fully investigated. In this study, the resin-cast scanning electron microscopy technique was used, for the first time, to image the lacuno-canalicular network within neoformed bone around bioactive glass (BG) particles implanted in rat tibia bone marrow. The most salient finding was that the osteocyte canaliculi pass through the calcium-phosphorus layer formed at the bone-BG interface and reach the silica-rich layer of the reacted BG.
骨-生物材料植入界面处的骨细胞陷窝-管道系统的形态尚未被充分研究。在这项研究中，首次使用树脂铸型扫描电子显微镜技术对植入大鼠骨髓的生物活性玻璃（BG）颗粒周围新形成的骨内的陷窝-管道网络进行成像。最显著的发现是，骨细胞的小管穿过在骨-BG 界面形成的钙磷层，并到达反应性 BG 的富含硅层。
