Department of Physiology, University of Split School of Medicine, Soltanska 2, 21 000 Split, Croatia.
Respir Physiol Neurobiol. 2010 Apr 30;171(2):165-70. doi: 10.1016/j.resp.2010.02.008. Epub 2010 Feb 24.
Recently, an increase in extravascular lung water (EVLW) accumulation with diminished left ventricular contractility within 60 min after SCUBA diving was reported. We have observed previously that diving was associated with reduced diffusing lung capacity for carbon monoxide (DLCO) and arterial oxygen pressure for up to 60-80 min postdive. Here we investigated whether increased EVLW persists 2-3h after successive deep dives in a group of seven male divers. The echocardiographic indices of pulmonary water accumulation (ultrasound lung comets (ULC)) and left ventricular function, respiratory functional measurements and arterial oxygen saturation (SaO(2)) were assessed 2-3h post diving, while venous gas bubbles (VGB) and the blood levels of NT-proBNP and proANP were analyzed 40 min after surfacing. Spirometry values, flow-volume, DLCO, SaO(2) and ULC were unchanged after each dive, except for significant increase in ULC after the second dive. Left ventricular function was reduced, while NT-proBNP and proANP levels were significantly elevated after majority of dives, suggesting a cardiac strain.
最近有报道称,在水肺潜水后 60 分钟内,会出现肺血管外水(EVLW)蓄积增加和左心室收缩功能降低。我们之前观察到潜水后 60-80 分钟内,弥散肺一氧化碳量(DLCO)和动脉血氧分压会降低。在这里,我们研究了一组 7 名男性潜水员连续深潜后 2-3 小时是否会持续存在 EVLW 增加的情况。潜水后 2-3 小时评估肺水蓄积的超声彗星尾征(ULC)和左心室功能的超声心动图指数、呼吸功能测量和动脉血氧饱和度(SaO(2)),而静脉气体泡(VGB)和 NT-proBNP 和 proANP 的血液水平则在浮出水面后 40 分钟进行分析。除了第二次潜水后 ULC 显著增加外,每次潜水后肺活量值、流量-容积、DLCO、SaO(2)和 ULC 均无变化。大多数潜水后左心室功能降低,而 NT-proBNP 和 proANP 水平显著升高,提示存在心脏应变。