Morin A, Denoroy L, Jouvet M
Département de Médecine Expérimentale, INSERM U 52-CNRS URA 1195, Université Claude Bernard, Lyon, France.
Brain Res. 1991 Jan 4;538(1):136-40. doi: 10.1016/0006-8993(91)90387-b.
The concentration of VIP-like immunoreactivity (VIP-LI) was determined by radioimmunoassay at various times of the day in 11 discrete brain areas and in the antehypophysis of rats maintained on a regular 12 h/12 h light-dark cycle. In the suprachiasmatic and periventricular nuclei the VIP-LI increased during the dark period and decreased during the subsequent light period. In addition, the VIP-LI exhibited complex variations in the locus coeruleus, the periaqueductal gray matter and the paraventricular nucleus, but did not change in the other areas investigated.
采用放射免疫分析法,在一天中的不同时间,对维持12小时光照/12小时黑暗规律循环的大鼠的11个离散脑区和垂体前叶中血管活性肠肽样免疫反应性(VIP-LI)的浓度进行了测定。在视交叉上核和室周核中,VIP-LI在黑暗期增加,在随后的光照期减少。此外,VIP-LI在蓝斑、导水管周围灰质和室旁核中表现出复杂的变化,但在所研究的其他区域中没有变化。