Laboratory for Stem Cell Biology, Riken Center for Developmental Biology, Kobe, 650-0047, Japan.
Immunity. 2010 Feb 26;32(2):143-4. doi: 10.1016/j.immuni.2010.02.007.
B cell receptor (BCR)-mediated tonic signals are important for B cell survival and development. In this issue of Immunity, Treanor et al. (2010) show that triggering of downstream responses is kept in check with BCR immobilization by actin.
B 细胞受体 (BCR) 介导的持续信号对于 B 细胞的存活和发育非常重要。在本期《免疫》中,Treanor 等人(2010 年)表明,通过肌动蛋白固定 BCR 可以控制下游反应的触发。