University of Mississippi School of Pharmacy, Jackson, Mississippi, USA.
J Hand Ther. 2010 Apr-Jun;23(2):230-6; quiz 237. doi: 10.1016/j.jht.2009.12.001. Epub 2010 Mar 1.
NARRATIVE REVIEW: Myopathy, fracture, tendon rupture, and neuropathy are severe physical adverse effects associated with commonly prescribed medications. Recognition of and exercise adjustment for these medication-induced effects by the therapist is essential to providing adequate care. The normal structure and function of muscle, tendon, cartilage, or bone may be altered by medications, leading to significant disability. The number of patients presenting to therapists with medication-induced physical complaints is rising with increases in medication utilization. Therapists should be involved in adverse effect risk reduction by 1) identification and reporting of potential adverse medication reactions, 2) adjustment of exercise regimen when the patient is on a medication with potential damaging effects on tendon, muscle, or cartilage, and 3) vigilant screening for medication-induced myopathies, fractures, neuropathies, and tendinopathies. Although many medications induce physical adverse effects, understanding the most serious musculoskeletal effects of commonly prescribed medications is critical for therapists.
叙述性回顾：肌病、骨折、肌腱断裂和神经病是与常用药物相关的严重身体不良反应。治疗师识别和调整这些药物引起的影响对于提供充分的护理至关重要。药物可能改变肌肉、肌腱、软骨或骨骼的正常结构和功能，导致严重残疾。随着药物使用的增加，因药物引起的身体不适而向治疗师就诊的患者数量正在增加。治疗师应通过以下方式参与降低不良反应风险：1）识别和报告潜在的药物不良反应，2）当患者正在使用可能对肌腱、肌肉或软骨造成损害的药物时，调整运动方案，3）警惕筛查药物引起的肌病、骨折、神经病和腱病。尽管许多药物会引起身体不良反应，但了解常用药物最严重的肌肉骨骼影响对治疗师来说至关重要。
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