Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.
Bioinformatics. 2010 Apr 15;26(8):1131-2. doi: 10.1093/bioinformatics/btq081. Epub 2010 Feb 25.
The central proteomics facilities pipeline (CPFP) provides identification, validation, and quantitation of peptides and proteins from LC-MS/MS datasets through an easy to use web interface. It is the first analysis pipeline targeted specifically at the needs of proteomics core facilities, reducing the data analysis load on staff, and allowing facility clients to easily access and work with their data. Identification of peptides is performed using multiple search engines, their output combined and validated using state-of-the-art techniques for improved results. Cluster execution of jobs allows analysis capacity to be increased easily as demand grows.
Released under the Common Development and Distribution License at http://cpfp.sourceforge.net/. Demonstration available at https://cpfp-master.molbiol.ox.ac.uk/cpfp_demo.
中央蛋白质组学设施管道 (CPFP) 通过易于使用的 Web 界面,从 LC-MS/MS 数据集提供肽和蛋白质的鉴定、验证和定量。它是第一个专门针对蛋白质组学核心设施需求的分析管道,减少了员工的数据分析负担,并允许设施客户轻松访问和处理他们的数据。肽的鉴定使用多个搜索引擎进行,其输出使用最先进的技术进行组合和验证,以提高结果的准确性。作业的集群执行允许随着需求的增长轻松增加分析能力。
根据通用开发和分发许可证发布,网址为 http://cpfp.sourceforge.net/。演示网址为 https://cpfp-master.molbiol.ox.ac.uk/cpfp_demo。