Negishi Mayumi, Shimomura Kenju, Proks Peter, Akuzawa Masako, Takahashi Masaki, Mori Masatomo, Shimomura Yohnosuke, Kobayashi Isao
Diabetes and Metabolic Disease Research Centre, Hidaka Hospital, Takasaki.
Intern Med. 2010;49(5):393-5. doi: 10.2169/internalmedicine.49.2843. Epub 2010 Mar 1.
The patient was a 69-year-old woman with a family history of type 2 diabetes. Her body mass index was 31.5. She was diagnosed as type 2 diabetes 32 years previously, and treated with insulin for 8 years. She had no episode of weight loss. She was hospitalized with diabetic ketoacidosis for the first time. Her GAD antibodies were not detected. However, ICA antibodies and insulin antibodies were positively detected. She was diagnosed with type 1 diabetes. Interestingly, her diabetes state was controlled to the same level after recovery from ketoacidosis.
该患者为一名69岁女性,有2型糖尿病家族史。她的体重指数为31.5。32年前她被诊断为2型糖尿病,曾接受胰岛素治疗8年。她没有体重减轻的情况。她首次因糖尿病酮症酸中毒住院。未检测到她的谷氨酸脱羧酶抗体。然而,胰岛细胞抗体和胰岛素抗体检测呈阳性。她被诊断为1型糖尿病。有趣的是,她从酮症酸中毒恢复后,糖尿病状态被控制在相同水平。