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肝癌射频消融术后门静脉血栓形成

Portal vein thrombosis after radiofrequency ablation of HCC.

作者信息

Orlacchio A, Mancini A, Calabrese G, Bolacchi F, Cozzolino V, Angelico M, Simonetti G

机构信息

Department of Diagnostic Imaging and Interventional Radiology, Tor Vergata University Hospital, Rome, Italy.

出版信息

Minerva Gastroenterol Dietol. 2010 Mar;56(1):87-91.

Abstract

The authors describe an unusual complication after radiofrequency ablation of hepatocellular carcinoma (HCC). An 84-year old man, already operated of right hepatectomy for HCC, underwent radiofrequency ablation (RFA) of a new focal hepatic lesion in IV segment, under ultrasound (US) and computed tomography (CT) guidance. The procedure was carried out without any special difficulties or complications. Seven days later, the patient suddenly complained epigastric pain, progressive jaundice and sleepiness and an increase in cholestasis sierological parameters. A CT scan revealed thrombosis of the left side branch of the portal vein, with moderate bile ducts distension. The case described demonstrates how RFA may cause thermally mediated damage of the surrounding structures, due to unpredictable radio-frequency propagation. The interest of this case report is due to the fact that portal vein thrombosis did not occur immediately after the procedure, it happened without direct vessel injury by the needle and involved a vessel greater than 3 mm.

摘要

作者描述了肝细胞癌(HCC)射频消融术后一种不寻常的并发症。一名84岁男性,此前已因HCC接受了右肝切除术,在超声(US)和计算机断层扫描(CT)引导下,对IV段新出现的肝脏局灶性病变进行了射频消融(RFA)。手术过程没有任何特殊困难或并发症。七天后,患者突然出现上腹部疼痛、进行性黄疸和嗜睡,胆汁淤积血清学参数升高。CT扫描显示门静脉左支血栓形成,伴有中度胆管扩张。所描述的病例表明,由于不可预测的射频传播,RFA可能会对周围结构造成热介导损伤。本病例报告的意义在于,门静脉血栓形成并非在手术后立即发生,它是在没有针直接损伤血管的情况下发生的,并且累及了直径大于3mm的血管。

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