Nat Rev Clin Oncol. 2010 Mar;7(3):130-2. doi: 10.1038/nrclinonc.2010.12.
The addition of hormonal therapy to radiation therapy improves survival in men with unfavorable risk prostate cancer. Yet, men with prostate cancer have higher rates of non-cancer death than the general population and most will die from causes other than their index malignancy. Co-morbid cardiovascular disease is strongly associated with cause of death and this raises the possibility that prostate cancer or its treatment increases cardiovascular disease risk and possibly mortality.
激素治疗联合放射治疗可改善预后不良的前列腺癌男性患者的生存率。然而,前列腺癌患者的非癌症死亡率高于一般人群,大多数患者将死于其主要恶性肿瘤以外的其他原因。合并心血管疾病与死亡原因密切相关,这提示前列腺癌或其治疗可能增加心血管疾病风险并可能导致死亡。