Herati Ramin S, Koh Joyce M, Gorospe Emmanuel C
Department of Medicine, Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
ScientificWorldJournal. 2010 Feb 17;10:298-300. doi: 10.1100/tsw.2010.36.
Sarcoidosis, a granulomatous disorder of unknown etiology, primarily affects the lungs and lymph nodes. Extrapulmonary disease without any pulmonary involvement is rare. Sarcoidosis with an elevated serum CA-125 level has only been reported five times in the literature. We describe a case of localized hepatosplenic sarcoidosis, confirmed by biopsy, with associated CA-125 elevation. In our review of the current literature, this is the first reported case of localized hepatosplenic sarcoidosis with associated serum CA-125 elevation.
结节病是一种病因不明的肉芽肿性疾病,主要累及肺部和淋巴结。无肺部受累的肺外疾病较为罕见。血清CA - 125水平升高的结节病在文献中仅报道过5次。我们描述了一例经活检证实的局限性肝脾结节病病例,伴有CA - 125升高。在我们对当前文献的回顾中,这是首例报道的伴有血清CA - 125升高的局限性肝脾结节病病例。