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[Helicobacter pylori infection in children with celiac disease].

作者信息

Ghimpu Silvia, Bozomitu Laura, Cârdei E, Oltean Carmen, Burlacu M, Anton Dana, Trandafir Laura, Mihăilă Doina, Moraru D

机构信息

Clinica a III-a Pediatrie, Facultatea de Medicina, Universitatea de Medicină si Farmacie "Gr.T. Popa" Iaşi.

出版信息

Rev Med Chir Soc Med Nat Iasi. 2009 Oct-Dec;113(4):1093-8.

Abstract

UNLABELLED

The purpose of this study is to evaluate symptomatology, endoscopic and histopathologic changes of Helicobacter pylori infection and gastritis lesions without Helicobacter pylori infection on children diagnosed with celiac disease.

MATERIAL AND METHOD

15 children under gluten-free diet were selected and, because of the recurrence of the dyspeptic syndrome, an upper digestive endoscopy associated with histopathologic exam was performed. Considering the histopathologic result we made two groups: first group (8 children with celiac disease and Helicobacter pylori infection) and second group (7 children with celiac disease without Helicobacter pylori infection, but associated with gastritis lesions).

RESULTS

The main symptom was diffuse abdominal pain in both groups. The endoscopic antrum aspects were congestive with striped aspect (first group--12.5%, second group--42.9%) and congestive with nodulation (first group--25%, second group--14.3%). The histopathologic diagnosis were: moderate active chronic pangastritis (first group--25%, second group--14.3%) moderate active chronic gastritis (first group--25%,second group--14.3%), lymphocytic gastritis (first group--12.5%, second group--14.3%).

CONCLUSION

The histopathologic exam remains the gold standard for celiac disease, gastritis lesions and Helicobacter pylori infection.

摘要

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