Baylor College of Dentistry, Dallas, TX, USA.
J Periodontol. 2010 Mar;81(3):435-41. doi: 10.1902/jop.2009.090393.
Minimally invasive surgery (MIS) is a surgical technique using very small incisions indicated for performing regenerative therapy in periodontal defects. The 11-month results from a prospective study of MIS were previously published. This article presents the 6-year results of that prospective study.
Patients from two private periodontal practices with advanced periodontitis who, after non-surgical therapy, had one or more sites with probing depths >or=6 mm were included in the study. An MIS surgical approach was used for all sites >or=6 mm. After surgical debridement, enamel matrix derivative (EMD) was placed into the bony defect. The surgical sites were reevaluated after >or=6 years.
Six-year data were available on 142 sites in 13 patients. No significant differences were noted in the results between the two offices, and the data were combined. Probing depths (mean: 3.18 mm; SD: 0.59 mm) and attachment levels (mean: 3.93 mm; SD: 0.19) at 6 years were unchanged from the 11-month measurements. No recession from preoperative levels was noted. All sites continued to be considered clinically successful.
The combination of MIS and EMD yielded significant reductions in probing depths and improvements in attachment levels while producing no detectable recession. The 11-month results remained stable at 6 years.
微创外科 (MIS) 是一种使用非常小的切口进行手术的技术，适用于在牙周缺损中进行再生治疗。先前已经发表了一项关于 MIS 的前瞻性研究的 11 个月结果。本文介绍了该前瞻性研究的 6 年结果。
本研究纳入了来自两家私人牙周诊所的患有晚期牙周炎的患者，这些患者在非手术治疗后，有一个或多个部位的探诊深度 >or=6 毫米。所有 >or=6 毫米的部位均采用 MIS 手术方法。在手术清创后，将釉基质衍生物 (EMD) 放置到骨缺损中。在 >or=6 年后对手术部位进行重新评估。
13 名患者的 142 个部位有 6 年的数据。两个诊所的结果没有显著差异，因此数据被合并。6 年时的探诊深度（平均值：3.18 毫米；标准差：0.59 毫米）和附着水平（平均值：3.93 毫米；标准差：0.19 毫米）与 11 个月时的测量值相比没有变化。没有从术前水平出现退缩。所有部位仍被认为临床成功。
MIS 和 EMD 的联合应用可显著降低探诊深度，并改善附着水平，同时不会导致可检测到的退缩。11 个月的结果在 6 年内保持稳定。
