Dong Bing, Zhu Yi-Min
Nanobiomedicine Division, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, Jiangsu 215125, P. R. China.
Chin J Cancer. 2010 Mar;29(3):340-5. doi: 10.5732/cjc.009.10313.
Molecular-targeted therapy is a newly developed approach for cancer therapy. With the advantages of lower side effects and higher performance, this approach has become a critical focus of cancer research. There are various molecules that can be treated as therapeutic targets for cancer. These molecules are located in different compartments of cancer cells, such as the cell membrane, cytoplasm, nuclei, and extracellular matrix. In this review, we mainly discussed the current progress in molecular-targeted therapy for cancers and the development of new drugs in this field.
分子靶向治疗是一种新开发的癌症治疗方法。这种方法具有副作用低、疗效高的优点，已成为癌症研究的关键焦点。有多种分子可被视为癌症的治疗靶点。这些分子位于癌细胞的不同区室，如细胞膜、细胞质、细胞核和细胞外基质。在本综述中，我们主要讨论了癌症分子靶向治疗的当前进展以及该领域新药的开发。
