Huang Yi-gao, Zhang Cao-jin, Huang Xin-sheng, Huang Tao, Huang Wen-hui
Department of Cardiology, Guangdong General Hospital, Guangzhou 510100, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Dec;37(12):1132-5.
To investigate the safety and efficacy of patent foramen ovale (PFO) closure with Left-disk-coated PFO occluder.
The device was implanted in patients with PFO under the guidance of fluoroscopy and transthoracal echocardiography using a 10-12 French delivery sheath via femoral vein approach. Aspirin (100 mg/d for 6 months) was administered post procedure. Patients were followed clinically and echocardiographically at 24 hours, 1 month, 3 months, 6 months, and 12 months after device implantation and yearly thereafter.
Permanent device implantation failed in one patient (4%) and succeed in the remaining 24 patients (96%). There were no major in-hospital-adverse events or complications (thromboembolism, occluder dislodgement, infection or myocardial infarction). Seven patients developed transient atrial premature beats or atrial tachycardia during implantation and stopped without medication post procedure. Follow-up [(25 + or - 12) months] results showed that all occluders were in position and there were no residual shunt, arrhythmia and cerebral vessel events post procedure.
Left-disk-coated PFO occluder is safe and effective for PFO closure.
探讨使用左盘涂层卵圆孔未闭封堵器闭合卵圆孔未闭（PFO）的安全性和有效性。
在透视和经胸超声心动图引导下，通过股静脉途径使用10-12法国输送鞘管将该装置植入PFO患者体内。术后给予阿司匹林（100mg/d，共6个月）。在装置植入后24小时、1个月、3个月、6个月和12个月以及此后每年对患者进行临床和超声心动图随访。
1例患者（4%）永久性装置植入失败，其余24例患者（96%）成功。无重大院内不良事件或并发症（血栓栓塞、封堵器移位、感染或心肌梗死）。7例患者在植入过程中出现短暂性房性早搏或房性心动过速，术后未用药即停止。随访[（25±12）个月]结果显示，所有封堵器位置良好，术后无残余分流、心律失常和脑血管事件。
左盘涂层PFO封堵器用于PFO闭合安全有效。
