Arrhythmia Section, Thorax Institute, Hospital Clínic, Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), University of Barcelona, Catalonia, Spain.
Heart Rhythm. 2010 May;7(5):612-8. doi: 10.1016/j.hrthm.2010.01.021. Epub 2010 Jan 22.
The best method for performing atrial fibrillation (AF) ablation is still under debate. The importance of using a circular mapping (CM) catheter for assessing isolation of the pulmonary vein (PV) antrum on the outcome of the procedure has not been clearly established.
The purpose of this study was to evaluate whether use of a CM catheter improves the arrhythmia-free proportion after circumferential pulmonary vein ablation (CPVA).
A series of 146 consecutive patients (83% males, age 53 +/- 10 years, 53% paroxysmal AF) were randomized to two ablation strategies. In both groups, ipsilateral PV encirclement was performed until disappearance or dissociation of the local electrogram within the surrounded area. In the first group, only the radiofrequency catheter was used to both map and ablate (CPVA group, n = 73). In the other group, a CM catheter was added to assess the electrical activity of the PV antrum (CPVA-CM group, n = 73). An ablation line along the left atrial roof was also created in all patients.
Procedural and fluoroscopic times were longer in the CPVA-CM group (P <.05). Severe procedure-related complications occurred in 1 (1.4%) patient in the CPVA group and in 3 (4.1%) patients in the CPVA-CM group (P = .317). After mean follow-up of 9 +/- 3 months, 31 (42.5%) patients in the CPVA group and 47 (64.4%) patients in the CPVA-CM group were arrhythmia-free without antiarrhythmic medication (P = .008).
Use of a CM catheter to ensure isolation of the PV antrum improved the success of CPVA but increased some procedural requirements.
目前对于心房颤动(AF)消融术的最佳方法仍存在争议。使用环形标测(CM)导管评估肺静脉(PV)窦部隔离对手术结果的重要性尚未明确。
本研究旨在评估在环肺静脉消融(CPVA)中使用 CM 导管是否能提高无心律失常比例。
连续纳入 146 例患者(83%为男性,年龄 53 ± 10 岁,53%为阵发性 AF),随机分为两组消融策略。两组均行同侧 PV 环绕消融,直至环绕区域内局部电图消失或分离。在第一组中,仅使用射频导管进行标测和消融(CPVA 组,n = 73)。在另一组中,添加 CM 导管以评估 PV 窦部的电活动(CPVA-CM 组,n = 73)。所有患者均行左房顶部消融线。
CPVA-CM 组的手术和透视时间较长(P <.05)。CPVA 组 1 例(1.4%)、CPVA-CM 组 3 例(4.1%)患者发生严重的手术相关并发症(P =.317)。平均 9 ± 3 个月随访后,CPVA 组 31 例(42.5%)和 CPVA-CM 组 47 例(64.4%)患者无心律失常且无需抗心律失常药物(P =.008)。
使用 CM 导管确保 PV 窦部隔离可提高 CPVA 的成功率,但增加了一些手术要求。