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高效抗逆转录病毒疗法(HAART)治疗合并严重精神疾病的HIV感染者的成本。

Cost of treating seriously mentally ill persons with HIV following highly active retroviral therapy (HAART).

作者信息

Rothbard Aileen B, Lee Sungeun, Blank Michael B

机构信息

School of Social Policy and Practice, University of Pennsylvania, Philadelphia, PA, USA.

出版信息

J Ment Health Policy Econ. 2009 Dec;12(4):187-94.

Abstract

BACKGROUND

Mounting evidence of high HIV prevalence rates among persons with serious mental illness underscores the importance of identifying and treating this population in order to prevent morbidity, mortality and the spread of the disease. Continual monitoring of services and costs is important for public health purposes to insure that persons with serious mental illness receive care for their HIV disorder that is at least comparable to those with HIV only and that the care is considered to be of equal quality.

AIM OF STUDY

This current study examines 2003 Medicaid expenditures associated with the treatment of adults with both serious mental illness and HIV, compared to those with HIV and serious mental illness only. The degree to which the occurrences of co-morbid conditions affect overall expenditures is examined, providing the first published co-morbidity expenditure ratios showing the additional cost burden associated with having these dual disorders. Also, changes in the composition of service costs for the co-morbid population are examined before and after the advent of newer antiretroviral and atypical antipsychotic medications.

METHODS

Study participants were adult Medicaid recipients age 19-64 with serious mental illness and HIV receiving services from a large urban city program in 2003. The expenditures were derived from Medicaid claims records. Differences between groups were compared using Chi-square and ANOVA tests of significance. To determine the relative cost burden of having a co-morbid versus a single disorder, a co-morbidity expenditure ratio was constructed using the total expenditure per person of those with a co-morbid disorder compared to the total expenditures of those with SMI-only and HIV-only. In order to determine the relative change in inpatient, outpatient and pharmacy service costs, the composition of service costs in 1996 is compared to the service cost composition in 2003 using the share of total costs that each service contributes.

RESULTS

In 2003, 788 persons with both SMI and HIV had the highest treatment expenditures at $23,842 per person followed by 2984 persons with HIV-only at $13,183, while the SMI-only group of 19,664 individuals was $11,860 per person. The comparison group had expenditures of $4,793 per person. The co-morbidity expenditure ratio in 2003 for the co-morbid population compared to the SMI-only group was 2.0 and 1.8 for the co-morbid population to the HIV-only population. Extensive redistribution of cost occurred between service categories in the co-morbid group between 1996 and 2003. The share of inpatient cost was reduced from 64% of total costs in 1996 to 30% of total cost in 2003. Conversely, the outpatient cost share increased from 17% of total costs in 1996 to 42% of total costs in 2003 as did the pharmacy share, which rose from 19% of total costs in 1996 to 27% of total costs in 2003.

DISCUSSION

Consistent with previous studies, the co-morbid group is a costly population with respect to treatment, despite the fact that inpatient care has decreased. The co-morbidity expenditure analysis indicates little cost saving associated with treating individuals with the co-morbid conditions compared to the cost of treating either conditions separately. This may suggest a lack of coordination or effective care management in the current system warranting further investigation. Also, we find no difference in the percent of the co-morbid population receiving HIV medication compared to the HIV population alone. This suggests that the co-morbid SMI population was being treated similarly to the HIV only group for their HIV disorders. Finally, though all groups had changes between 1996 and 2003 in the proportion of expenditures allocated to each of the service categories, the redistribution of cost between inpatient and outpatient care was the greatest in the co-morbid group.

IMPLICATIONS FOR FUTURE RESEARCH

Although the study data suggests that individuals with both HIV and serious mental illness are receiving similar treatment for their HIV disorder as those with HIV alone, a concern that requires further investigation is the finding that HAART treatment is being used by less than 50% of the co-morbid and HIV only study population. Further investigation is required to determine the reason for the relatively low utilization of HAART medications in both HIV groups. Also, the use of a co-morbidity expenditure ratio offers a promising approach for comparing the cost burden associated with multiple disorders.

摘要

背景

越来越多的证据表明,严重精神疾病患者中艾滋病毒的高流行率凸显了识别和治疗这一人群以预防发病、死亡和疾病传播的重要性。持续监测服务和成本对于公共卫生目的很重要,以确保患有严重精神疾病的人能够获得针对其艾滋病毒疾病的护理,这种护理至少与仅感染艾滋病毒的人相当,并且被认为具有同等质量。

研究目的

本研究调查了2003年与同时患有严重精神疾病和艾滋病毒的成年人治疗相关的医疗补助支出,并与仅患有艾滋病毒和严重精神疾病的成年人进行了比较。研究考察了共病状况的发生对总支出的影响程度,提供了首个已发表的共病支出比率,显示了患有这两种双重疾病所带来的额外成本负担。此外,还研究了新型抗逆转录病毒药物和非典型抗精神病药物出现前后共病群体服务成本构成的变化。

方法

研究参与者为2003年年龄在19 - 64岁、患有严重精神疾病和艾滋病毒并从一个大型城市项目接受服务的成年医疗补助受助人。支出数据来自医疗补助理赔记录。使用卡方检验和方差分析显著性检验比较组间差异。为了确定患有共病与单一疾病的相对成本负担,构建了共病支出比率,即使用患有共病疾病者的人均总支出与仅患有严重精神疾病者和仅患有艾滋病毒者的总支出进行比较。为了确定住院、门诊和药房服务成本的相对变化,使用每项服务在总成本中所占份额,将1996年的服务成本构成与2003年的服务成本构成进行比较。

结果

2003年,788名同时患有严重精神疾病和艾滋病毒的人治疗支出最高,人均23,842美元,其次是2984名仅患有艾滋病毒的人,人均13,183美元,而19,664名仅患有严重精神疾病的人群人均支出为11,860美元。对照组人均支出为4,793美元。2003年,与仅患有严重精神疾病的人群相比,共病群体的共病支出比率为2.0,与仅患有艾滋病毒的人群相比为1.8。1996年至2003年期间,共病组服务类别之间发生了广泛的成本重新分配。住院成本在总成本中的占比从1996年的64%降至2003年的30%。相反,门诊成本份额从1996年占总成本的17%增至2003年的42%,药房成本份额也从1996年占总成本的19%升至2003年的27%。

讨论

与先前研究一致,尽管住院护理有所减少,但共病群体在治疗方面成本高昂。共病支出分析表明,与分别治疗两种疾病的成本相比,治疗患有共病状况的个体几乎没有节省成本。这可能表明当前系统中缺乏协调或有效的护理管理,值得进一步调查。此外,我们发现共病群体中接受艾滋病毒药物治疗的百分比与仅感染艾滋病毒的群体相比没有差异。这表明患有严重精神疾病的共病群体在治疗其艾滋病毒疾病方面与仅患有艾滋病毒的群体类似。最后,尽管所有组在1996年至2003年期间分配给每个服务类别的支出比例都有变化,但共病组住院和门诊护理之间的成本重新分配最大。

对未来研究的启示

尽管研究数据表明,同时患有艾滋病毒和严重精神疾病的个体在治疗其艾滋病毒疾病方面与仅患有艾滋病毒的个体类似,但一个需要进一步调查的问题是,发现不到50%的共病群体和仅患有艾滋病毒的研究人群使用高效抗逆转录病毒疗法(HAART)治疗。需要进一步调查以确定两个艾滋病毒组中HAART药物使用率相对较低的原因。此外,使用共病支出比率为比较与多种疾病相关的成本负担提供了一种有前景的方法。

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