Department of Social Welfare, Pusan National University, 30 Jangjeon-dong, Geumjung-gu, Busan, 609-735, South Korea,
Adm Policy Ment Health. 2011 Sep;38(5):335-44. doi: 10.1007/s10488-010-0320-1.
Persons with serious mental illness (SMI) have higher rates of co-morbid HIV disorders compared to the general population. There are concerns that the SMI/HIV population may be receiving fewer HIV and psychotropic medications due to problems of access and concerns by providers associated with following complex medication regimes. The purpose of this study was to examine any disparity in medication treatment of the SMI/HIV population by comparing medication use and continuity of prescription fills to groups that had HIV or SMI only versus those with SMI/HIV. Study participants were adult Medicaid recipients aged 19-64 with serious mental illness and HIV receiving services in Philadelphia from 2002 through 2003. Differences between the groups in case mix characteristics, medication use rates, and continuity of psychotropic and antiretroviral medication use were compared using Chi-square, t-tests of significance, and logistic regression. Co-morbid individuals were as likely to have filled prescriptions for psychotropic and antiretroviral medications as those with a single disorder and equally persistent in their continuity of antiretroviral medication refills as those with HIV only. However, persons with co-morbid condition had lower continuity of psychotropic medication use compared to those with SMI only. Our findings suggest the need to develop an integrated medical and behavioral healthcare model to improving coordination and treatment for patients with co-occurring disorders. Future research is warranted to investigate the reasons for the discrepancy in continuity of psychotropic adherence for the SMI/HIV population.
患有严重精神疾病(SMI)的人比一般人群更容易同时患有 HIV 疾病。有人担心,由于获得药物的机会有限,以及提供者对遵循复杂药物治疗方案的担忧,SMI/HIV 人群可能会接受较少的 HIV 和精神药物治疗。本研究的目的是通过比较仅患有 HIV 或 SMI 以及同时患有 SMI/HIV 的患者的药物使用和处方填写的连续性,来检查 SMI/HIV 人群在药物治疗方面是否存在差异。研究参与者是在费城接受服务的年龄在 19 至 64 岁之间的成年医疗补助受助人,患有严重精神疾病和 HIV。使用卡方检验、显著性 t 检验和逻辑回归比较了组间病例组合特征、药物使用率以及精神药物和抗逆转录病毒药物使用的连续性差异。共病患者与仅患有单一疾病的患者一样有可能开精神药物和抗逆转录病毒药物的处方,并且在抗逆转录病毒药物续用时同样坚持用药。然而,与仅患有 SMI 的患者相比,共病患者的精神药物使用连续性较低。我们的研究结果表明,需要开发一种综合的医疗和行为健康护理模式,以改善共病患者的协调和治疗。未来的研究需要调查 SMI/HIV 人群在精神药物治疗依从性连续性方面存在差异的原因。