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[植物状态(长期昏迷)作为稳定病理状态的表现]

[Vegetative state (prolonged coma) as manifestation of stable pathological state].

作者信息

Vaĭnshenker Iu I, Ivchenko I M, Korotkov A D, Meliucheva L A, Kataeva G V, Medvedev S V

出版信息

Fiziol Cheloveka. 2010 Jan-Feb;36(1):138-41.

Abstract

Complex examination of 25 patients in vegetative state was performed before and after correction of secondary brain damage. Catamnesis over a period of at least 6 months was traced. Preliminary results showed that better recovery of consciousness and cognitive functions was observed if before treatment diffuse glucose hypometabolism was significantly more widespread than morphological changes. Minimal positive dynamics was detected in cases in which the reduction of glucose metabolism was minimal. This and other paradoxical results become explainable if to consider vegetative state as stable pathological state of the brain. This open new approaches to treatment of this group of patients.

摘要

对25例植物人状态患者在继发性脑损伤纠正前后进行了综合检查。追踪了至少6个月的病史。初步结果显示,如果治疗前弥漫性葡萄糖代谢减低比形态学改变明显更广泛,则意识和认知功能的恢复更好。在葡萄糖代谢降低最小的病例中检测到最小的正向动态变化。如果将植物人状态视为大脑的稳定病理状态,那么这一结果以及其他矛盾的结果就变得可以解释了。这为治疗这组患者开辟了新的途径。

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