Department of Neurological Surgery, University of California, San Francisco, California 94143, USA.
Neurosurg Focus. 2010 Mar;28(3):E5. doi: 10.3171/2010.1.FOCUS09288.
The authors review the literature on the treatment of spinal deformity in patients with Parkinson disease (PD) and formulate a treatment algorithm.
The authors provide representative cases of patients with PD and spinal deformity who underwent deep brain stimulation (DBS) or spinal surgery.
In patients with PD and spinal deformity who undergo spinal surgery there is a high rate of acute and delayed complications. Patients who undergo DBS, while having significantly fewer complications, often do not regain sagittal balance.
Cases involving PD and camptocormia have a high rate of complications when spinal surgery is performed. The authors prefer to offer spinal surgery only to patients with coexisting spinal stenosis causing radiculopathy or myelopathy. Patients with PD and camptocormia without spinal stenosis may be considered for DBS, but the results are mixed.
作者回顾了有关帕金森病(PD)患者脊柱畸形治疗的文献,并制定了治疗算法。
作者提供了接受脑深部电刺激(DBS)或脊柱手术的 PD 伴脊柱畸形患者的典型病例。
接受脊柱手术的 PD 伴脊柱畸形患者有很高的急性和迟发性并发症发生率。接受 DBS 的患者虽然并发症明显较少,但往往无法恢复矢状位平衡。
当进行脊柱手术时,涉及 PD 和驼背畸形的病例并发症发生率很高。作者更倾向于仅为合并引起神经根病或脊髓病的脊柱狭窄症的患者提供脊柱手术。对于无脊柱狭窄症的 PD 伴驼背畸形患者,可考虑进行 DBS,但结果不一。