Department of Microbiology, Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, VIC 3800, Australia.
Vet Microbiol. 2010 Jul 29;144(1-2):1-17. doi: 10.1016/j.vetmic.2010.01.027. Epub 2010 Feb 4.
Pasteurella multocida is a ubiquitous pathogen which causes a range of diseases in diverse animal species. Components of the bacterial outer membrane, such as trans membrane proteins and lipoproteins, play key roles in the interaction of the pathogen with the host environment and in the host immune response to infection. In this review, we evaluate the current knowledge of P. multocida outer membrane proteins and their role in pathogenesis and immunity.
多杀巴斯德菌是一种无处不在的病原体,可导致多种动物物种发生一系列疾病。细菌外膜的组成部分,如跨膜蛋白和脂蛋白,在病原体与宿主环境的相互作用以及宿主对感染的免疫反应中发挥着关键作用。在这篇综述中,我们评估了多杀巴斯德菌外膜蛋白的现有知识及其在发病机制和免疫中的作用。