Sigmundsson Thórir Svavar, Gunnarsson Björn, Benediktsson Sigurdur, Gunnarsson Gunnar Thór, Dúason Sveinbjörn, Thorgeirsson Gestur
Laeknabladid. 2010 Mar;96(3):159-65. doi: 10.17992/lbl.2010.03.278.
A good outcome of patients presenting with STEMI (ST-Segment Elevation Myocardial Infarction) depends on early restoration of coronary blood flow. Pre-hospital fibrinolysis is recommended if primary percutaneous coronary intervention (PPCI) cannot be performed within 90 minutes of first medical contact (FMC). The purpose of this study was to study transport times for patients with STEMI who were transported with air-ambulance from the northern rural areas of Iceland to Landspitali University Hospital in Reykjavík, and to assess if the medical management was in accordance with clinical guidelines.
Retrospective chart review identified 33 patients with STEMI who were transported with air-ambulance to Landspitali University Hospital in Reykjavík during the years 2007 and 2008.
The total time from first medical contact to arrival at Landspitali University Hospital emergency room was 3 hours and 7 minutes (median). All patients received aspirin and 26 (78.8%) received clopidogrel and enoxaparin. 16 patients (48.5%) received thrombolytic therapy in median 33 minutes after FMC and 15 patients had PPCI performed in median 4 hours and 15 minutes after FMC. Estimated PCI related delay was 3 hours and 42 minutes (median). One patient died and one was resuscitated within 30 hospital days. Mean hospital stay was 6.0 days.
First medical contact to balloon time of less than 90 minutes is impossible for patients with STEMI transported from the northern rural areas to Landspitali University Hospital in Reykjavík. Medical therapy was in many cases suboptimal and PCI related delay too long.
ST段抬高型心肌梗死(STEMI)患者的良好预后取决于冠状动脉血流的早期恢复。如果在首次医疗接触(FMC)后90分钟内无法进行直接经皮冠状动脉介入治疗(PPCI),则建议进行院前溶栓治疗。本研究的目的是研究从冰岛北部农村地区通过空中救护车转运至雷克雅未克市Landspitali大学医院的STEMI患者的转运时间,并评估医疗管理是否符合临床指南。
通过回顾性病历审查,确定了2007年至2008年间33例通过空中救护车转运至雷克雅未克市Landspitali大学医院的STEMI患者。
从首次医疗接触到抵达Landspitali大学医院急诊室的总时间为3小时7分钟(中位数)。所有患者均接受了阿司匹林治疗,26例(78.8%)接受了氯吡格雷和依诺肝素治疗。16例患者(48.5%)在FMC后中位数33分钟接受了溶栓治疗,15例患者在FMC后中位数4小时15分钟接受了PPCI治疗。估计PCI相关延迟为3小时42分钟(中位数)。1例患者死亡,1例在住院30天内进行了复苏。平均住院时间为6.0天。
对于从冰岛北部农村地区转运至雷克雅未克市Landspitali大学医院的STEMI患者,首次医疗接触到球囊扩张时间不可能少于90分钟。在许多情况下,药物治疗并不理想,PCI相关延迟过长。