Hellquist H B, Lundgren J
Department of Pathology, Orebro Medical Centre Hospital, Sweden.
J Laryngol Otol. 1991 Mar;105(3):186-90. doi: 10.1017/s0022215100115312.
Five cases of a rare malignant sinonasal tumour of neurofibromatous nature are described. The term neurogenic sarcoma (or malignant peripheral nerve sheath tumour) is advocated instead of malignant schwannoma. The clinicopathological features of this tumour are described, and the different diagnosis are discussed. The necessity of using immunohistochemistry in the diagnosis of sinonasal tumours of fibromatous nature is emphasized. The clinical management consists of radical surgery and adjuvant radiotherapy. Clinically there seems to be a high-grade and a low-grade type of sinonasal neurogenic sarcoma, however, this could not be distinguished histologically in the present series.
本文描述了5例具有神经纤维瘤性质的罕见鼻窦恶性肿瘤。提倡使用术语神经源性肉瘤（或恶性周围神经鞘膜瘤）而非恶性施万细胞瘤。描述了该肿瘤的临床病理特征，并讨论了不同的诊断方法。强调了免疫组织化学在诊断纤维瘤性质鼻窦肿瘤中的必要性。临床治疗包括根治性手术和辅助放疗。临床上似乎存在高级别和低级别类型的鼻窦神经源性肉瘤，然而，在本系列中无法从组织学上进行区分。
