Porjazova E, Zaprjanov Z, Batashki I, Markova D, Milchev N
Akush Ginekol (Sofiia). 2009;48(2):26-8.
Uterine carcinosarcomas are highly aggressive malignant tumours, consisting of both epithelial and mesenchymal components. They represent 1-3% of the malignant uterine neoplasms. Their histogenesis is unclear. Because of their rarity and the very few clinical data available, the studies of potential therapeutic goals are scarce. We present clinical and pathohistological description of a rare case of a 76-year-old woman with a uterine carcinosarcoma with a chondroid differentiation, examined immunohistochemically with Cytokeratin, Vimentin and S-100 protein.
子宫癌肉瘤是极具侵袭性的恶性肿瘤,由上皮和间充质成分组成。它们占子宫恶性肿瘤的1%-3%。其组织发生尚不清楚。由于其罕见性以及可用的临床数据极少,关于潜在治疗靶点的研究也很匮乏。我们呈现了一例76岁患有伴有软骨样分化的子宫癌肉瘤的罕见病例的临床和病理组织学描述,并采用细胞角蛋白、波形蛋白和S-100蛋白进行了免疫组化检查。