Haidar Rachid, Najjar Marc, Der Boghossian Asdghig, Tabbarah Zuhair
Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
Scand J Infect Dis. 2010 Jul;42(6-7):405-11. doi: 10.3109/00365540903582459.
Propionibacterium acnes was previously considered a contaminant and its role in spine infection has been understated. Although rare, such infections are present especially after instrumented spine surgery. They are usually delayed and hard to diagnose. Delayed infection should be suspected in patients with pain and a history of spine surgery. In this article, we review the diagnostic challenges associated with delayed P. acnes infection after spine surgery, guided by relevant studies in the literature. The medical databases of PubMed, Medline and Embase were searched for the literature on delayed spine infections and osteomyelitis following spinal procedures. The medical literature was reviewed for articles published between 1955 and 2008. Our review of the literature revealed 13 cases of P. acnes osteomyelitis following surgical procedures involving the spine. We also present a clinical case of delayed P. acnes osteomyelitis following discectomy and fusion with instrumentation.
痤疮丙酸杆菌以前被认为是一种污染物，其在脊柱感染中的作用一直被低估。尽管此类感染罕见，但尤其在脊柱内固定手术后会出现。它们通常出现较晚且难以诊断。有疼痛症状且有脊柱手术史的患者应怀疑有延迟感染。在本文中，我们以文献中的相关研究为指导，回顾了脊柱手术后痤疮丙酸杆菌延迟感染相关的诊断挑战。我们在PubMed、Medline和Embase医学数据库中搜索了有关脊柱手术后延迟性脊柱感染和骨髓炎的文献。对1955年至2008年发表的医学文献进行了综述。我们对文献的综述发现了13例涉及脊柱手术的痤疮丙酸杆菌骨髓炎病例。我们还展示了一例椎间盘切除并融合内固定术后痤疮丙酸杆菌延迟性骨髓炎的临床病例。
