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耻骨联合分离作为剖宫产的独立危险因素。

Symphysiolysis as an independent risk factor for cesarean delivery.

作者信息

Lebel David E, Levy Amalia, Holcberg Gershon, Sheiner Eyal

机构信息

Department of Orthopedics, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, Be'er-Sheva, Israel.

出版信息

J Matern Fetal Neonatal Med. 2010 May;23(5):417-20. doi: 10.3109/14767050903420291.

Abstract

OBJECTIVES

To investigate whether symphysiolysis during pregnancy is a risk factor for cesarean delivery (CD).

METHODS

A retrospective population-based study comparing all singleton pregnancies of women with and without symphysiolysis was conducted. Deliveries occurred between the years 2000 and 2007. Multiple logistic regression models were used to control for confounders.

RESULTS

Out of 80,898 patients, 0.2% (n = 154) were diagnosed with symphysiolysis during pregnancy. Patients with symphysiolysis were significantly older as compared to the comparison group. These patients had higher rates of mild pre-eclampsia, gestational diabetes mellitus (GDM) and labor induction as compared to patients without symphysiolysis. Higher rates of CD were noted in pregnancies complicated by symphysiolysis [22.1% vs. 15.9%; Odds ratio (OR) = 1.5, 95% confidence interval (CI) 1.02-2.2; P = 0.036]. Using multiple logistic regression model, with symphysiolysis as the outcome variable, controlling for labor induction, mild pre-eclampsia and GDM, symphysiolysis was noted as an independent risk factor for CD (weighted OR = 1.7, 95% CI 1.1-2.5; P = 0.009). Perinatal outcomes such as low Apgar scores (<7) at 1 and 5 min and perinatal mortality were comparable between the groups.

CONCLUSIONS

Symphysiolysis is an independent risk factor for CD.

摘要

目的

探讨孕期耻骨联合分离是否为剖宫产的危险因素。

方法

开展一项基于人群的回顾性研究,比较有和没有耻骨联合分离的女性的所有单胎妊娠情况。分娩发生在2000年至2007年之间。使用多重逻辑回归模型控制混杂因素。

结果

在80898例患者中,0.2%(n = 154)在孕期被诊断为耻骨联合分离。与对照组相比,耻骨联合分离患者年龄显著更大。与无耻骨联合分离的患者相比,这些患者轻度子痫前期、妊娠期糖尿病(GDM)和引产的发生率更高。耻骨联合分离合并妊娠的剖宫产率更高[22.1%对15.9%;优势比(OR)= 1.5,95%置信区间(CI)1.02 - 2.2;P = 0.036]。以耻骨联合分离作为结果变量,使用多重逻辑回归模型,控制引产、轻度子痫前期和GDM,耻骨联合分离被视为剖宫产的独立危险因素(加权OR = 1.7,95% CI 1.1 - 2.5;P = 0.009)。两组间1分钟和5分钟时低Apgar评分(<7)及围产儿死亡率等围产儿结局相当。

结论

耻骨联合分离是剖宫产的独立危险因素。

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