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辅助性髂内支架可降低 Zenith 支架移植物治疗腹主动脉瘤腔内修复术后支架移植物支闭塞的风险。

Adjunctive iliac stents reduce the risk of stent-graft limb occlusion following endovascular aneurysm repair with the Zenith stent-graft.

机构信息

Regional Vascular Unit and, Royal Liverpool University Hospital, Liverpool L7 8XP, UK.

出版信息

J Endovasc Ther. 2010 Feb;17(1):108-14. doi: 10.1583/09-2854.1.

Abstract

PURPOSE

To determine whether the introduction of a policy of adjunctive stent insertion based on preoperative CT assessment or completion angiography reduced the incidence of limb occlusion after stent-graft implantation for endovascular aneurysm repair (EVAR).

METHODS

A tertiary referral unit's endovascular database was retrospectively interrogated to compare the incidence of endograft limb occlusion in Zenith grafts following the introduction of a policy of selective adjunctive stent insertion. Group A included 288 limbs at risk in 146 patients (134 men; mean age 74+/-8 years) treated prior to August 2005 in whom adjunctive stents were inserted on an ad hoc basis only. Group B included 293 limbs at risk in 149 patients (127 men; mean age 76+/-7 years) treated after this date in whom a more aggressive adjunctive stenting strategy was adopted. Kaplan-Meier analysis was employed to compare outcomes.

RESULTS

In total, 295 patients underwent EVAR involving 581 iliac vessels, of which 11 (1.8%) occluded at a median of 24 months (0-27). Of 65 limbs extended into the external iliac segment, 5 (7.6%) subsequently occluded; in the remaining 516 limbs, there were 6 (1.1%) occlusions (p = 0.004). Across the study group, 38 (6.5%) adjunctive stents were deployed in limbs deemed at risk; 1 (2.6%) of these occluded. In the remaining 543 unstented limbs, 10 (1.8%) occlusions occurred (p = 0.15). There were 11 occlusions in group A, in which 5 (1.7%) adjunctive stents had been deployed, but none in group B, which had received 33 (11.2%) stents (p<0.0001). Kaplan-Meier survival curves identified primary patency rates at 36 months of 96% and 100%, respectively (p = 0.001).

CONCLUSION

Adjunctive stenting significantly reduces the risk of postoperative stent-graft limb occlusion without obvious compromise to the aneurysm repair.

摘要

目的

确定基于术前 CT 评估或完成血管造影的辅助支架置入术的引入是否降低了血管内动脉瘤修复(EVAR)后支架移植物植入后的肢体闭塞发生率。

方法

回顾性询问三级转诊单位的血管内数据库,比较引入选择性辅助支架置入术的政策后,Zenith 移植物内的移植物分支闭塞的发生率。A 组包括 288 个肢体,涉及 146 例患者(134 例男性;平均年龄 74+/-8 岁),这些患者在 2005 年 8 月之前接受治疗,仅在特殊情况下插入辅助支架。B 组包括 293 个肢体,涉及 149 例患者(127 例男性;平均年龄 76+/-7 岁),这些患者在这之后接受治疗,采用了更积极的辅助支架置入策略。采用 Kaplan-Meier 分析比较结果。

结果

共有 295 例患者接受了涉及 581 个髂血管的 EVAR,其中 11 例(1.8%)在中位数为 24 个月(0-27)时闭塞。在延长至外部髂段的 65 个肢体中,有 5 个(7.6%)随后闭塞;在其余 516 个肢体中,有 6 个(1.1%)闭塞(p=0.004)。在整个研究组中,在被认为有风险的肢体中放置了 38 个(6.5%)辅助支架;其中 1 个(2.6%)闭塞。在其余 543 个未放置支架的肢体中,有 10 个(1.8%)闭塞(p=0.15)。A 组有 11 个闭塞,其中 5 个(1.7%)放置了辅助支架,但 B 组没有,B 组放置了 33 个(11.2%)支架(p<0.0001)。Kaplan-Meier 生存曲线确定 36 个月时的主要通畅率分别为 96%和 100%(p=0.001)。

结论

辅助支架置入术可显著降低术后支架移植物分支闭塞的风险,同时对动脉瘤修复无明显影响。

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