Department of Specialistic Surgeries and Anesthesiological Sciences, University of Bologna, Policlinico S Orsola-Malpighi, Bologna, Italy.
J Endovasc Ther. 2011 Aug;18(4):585-90. doi: 10.1583/11-3467.1.
To evaluate the role of 3-projection completion angiography in defining endograft limb stenosis after endovascular aneurysm repair (EVAR) and to determine the role of adjunctive stenting in reducing the risk of endograft limb occlusion.
In our center, stent-graft limb dilation was routinely done after endograft deployment in patients with preoperatively identified severe iliac axis angulation to reduce the incidence of limb stenosis. Completion angiography was then routinely performed in anteroposterior (AP) and 45° right and left oblique projections to identify perioperative endograft limb stenosis after the stiff guidewires were removed. Adjunctive stenting was used in iliac limbs with postangioplasty residual stenosis >50%. From January 2005 to November 2010, 302 EVAR patients (296 men; mean age 74.25 ± 7.04 years, range 53-90) with 589 stent-graft limbs (aortomonoiliac stent-graft in 15 patients) who had a minimum 6 months of follow-up and a nonstenotic aortic bifurcation were selected for this study. Patient demographics, clinical risk factors, iliac anatomical features, procedure data, and limb patency were analyzed. Primary endpoints were the incidence of limb stenosis >50% and any associated risk factors; the secondary endpoint was the primary patency of stent-graft limbs with adjunctive stenting.
On 3-projection completion angiography, 40 (6.8%) limbs presented limb stenosis and were treated with adjunctive stenting; in only 28 (70%) of these cases was the >50% limb stenosis evident on the AP view. According to the degree of preoperative iliac angulation, limb stenosis occurred in mild (<60°), moderate (60°-89°), and severe (≥ 90°) angulations in 14 (4.6%), 9 (5.6%), and 17 (13.4%) cases, respectively; positive predictors for limb stenosis were severe iliac artery angulation [vs. moderate (p = 0.02) and mild (p = 0.001)] and stent-graft limb diameter <16 mm (p = 0.02). In the adjunctive stenting group, the mean follow-up was 16.1 months; no graft occlusion, graft erosion, or restenosis was seen during follow-up (100% primary patency at 12 and 24 months).
Three-projection completion angiography is crucial to identifying limb stenosis, for which adjunctive stenting appears to ensure primary patency in midterm follow-up. Preoperative iliac artery angulation and small endograft limb diameter are positive prognostic factors for limb stenosis >50%.
评估 3 投影完成血管造影术在血管内动脉瘤修复(EVAR)后定义血管内移植物分支狭窄的作用,并确定辅助支架置入在降低血管内移植物分支闭塞风险中的作用。
在我们中心,在术前识别出严重的髂轴成角的患者中,在血管内移植物部署后常规进行支架移植物分支扩张,以降低分支狭窄的发生率。然后在前后位(AP)和 45°右和左斜位投影上常规进行完成血管造影,以在移除硬导丝后识别围手术期血管内移植物分支狭窄。在血管成形术后残余狭窄>50%的髂肢中使用辅助支架置入。2005 年 1 月至 2010 年 11 月,选择了 302 名接受 EVAR 治疗(296 名男性;平均年龄 74.25±7.04 岁,范围 53-90)且至少有 6 个月随访期且无狭窄主动脉分叉的患者进行这项研究,共 589 个支架移植物分支(15 名患者为主动脉单髂支架移植物)。分析了患者人口统计学、临床危险因素、髂解剖特征、手术数据和分支通畅情况。主要终点是分支狭窄>50%的发生率和任何相关危险因素;次要终点是辅助支架置入后支架移植物分支的原发性通畅率。
在 3 投影完成血管造影中,40 个(6.8%)分支出现分支狭窄,并接受了辅助支架置入治疗;在这些病例中,只有 28 例(70%)在 AP 视图上显示了>50%的分支狭窄。根据术前髂动脉成角程度,分支狭窄发生在轻度(<60°)、中度(60°-89°)和重度(≥90°)成角的患者中分别为 14 例(4.6%)、9 例(5.6%)和 17 例(13.4%);分支狭窄的阳性预测因素为严重的髂动脉成角[与中度(p=0.02)和轻度(p=0.001)相比]和支架移植物分支直径<16mm(p=0.02)。在辅助支架置入组中,平均随访时间为 16.1 个月;在随访期间未发生移植物闭塞、移植物侵蚀或再狭窄(12 个月和 24 个月时 100%的原发性通畅率)。
3 投影完成血管造影术对于识别分支狭窄至关重要,辅助支架置入术似乎可以确保中期随访的原发性通畅率。术前髂动脉成角和小的血管内移植物分支直径是分支狭窄>50%的阳性预测因素。