Szumera-Ciećkiewicz Anna, Ptaszyński Konrad, Pawełas Andrzej, Rutkowski Piotr
Department of Pathology, Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, ul. Roentgena 5, 02-781 Warszawa.
Pol J Pathol. 2009;60(4):193-8.
One of the most unusual and uncommon types of osteomalacia is the oncogenic osteomalacia that is predominantly caused by a soft tissue or bone tumour, mostly by a phosphaturic mesenchymal tumour, mixed connective tissue type (PMTMCT). We report a case of a 27-year-old male presented with complaints of progressive and generalized muscle weakness, bone pains and multiple fractures. Intra-articular PMTMCT of the knee was diagnosed and surgically removed. We describe histopathological features of PMTMCT and review the most recent studies concerning this diagnostic problem.
最罕见且不常见的骨软化症类型之一是肿瘤性骨软化症,其主要由软组织或骨肿瘤引起,多数情况下是由混合型结缔组织性磷尿性间叶肿瘤(PMTMCT)所致。我们报告了一例27岁男性患者,其主诉为进行性全身性肌无力、骨痛和多处骨折。经诊断为膝关节内PMTMCT,并进行了手术切除。我们描述了PMTMCT的组织病理学特征,并回顾了有关这一诊断问题的最新研究。